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filingDate 1993-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35b1ce3884d1bbaa016231fe8fe34259
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publicationDate 1994-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9403626-A1
titleOfInvention Method of highly purifying human serum albumin
abstract A method of highly purifying human serum albumin (HSA) which comprises bringing a fraction containing HSA produced by gene manipulation into contact with a chelate chromatography carrier having copper ions combined therewith and eluting the HSA adsorbed on the carrier by using a buffer having a pH of 5 to 7 and containing ammonium chloride as an antagonist. This method can provide a highly pure HSA free from yeast-origin components which have been dificult to remove satisfactorily by the conventional method of purifying HSA produced by gene manipulation.
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