| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9795f7c6e5b5ce14b031c12c7850f75d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb5181e825bf4d3a308d7ec4c3ab67f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_291f56b4a35097fb62c086ba2d72caf7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_461972d20f07e90a5c6aa4e898a899cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1993-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a23c764371d40a51cc99452a60ea1fb9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b61b25e9986ccc437b0447315674ee5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12cbf714fbabb94d418eac491d4bc8e4 |
| publicationDate |
1994-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9402589-A1 |
| titleOfInvention |
Mammalian cationic proteins having lipopolysaccharide binding and anti-coagulant activity |
| abstract |
Compositions and methods for the treatment and diagnosis of lipopolysaccharide-related conditions and coagulant-related disease are provided. Compositions include polypeptides which are identical or homologous to a certain cationic protein (CAP18) obtained from mammalian granulocytes, particularly including a reactive nitrogen inhibiting peptide (RNIP) fragment found at the carboxy-terminus of CAP18. Polypeptides are capable of binding to LPS and inhibiting LPS-mediated activation of macrophage, as well as interfering with the clotting cascade to inhibit coagulation in conditions such as disseminated intravascular coagulation. Compositions comprising the polypeptides in a suitable pharmaceutical carrier are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6025326-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7071293-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02095076-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02095076-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6159936-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6440690-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-684170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5994306-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6103888-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6040291-A |
| priorityDate |
1992-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |