| abstract |
A compound of formula (I) wherein R1 and R2 each represents a hydrogen atom or an alkyl group, Z represents a ring selected from formula (II) in which n represents 4, 5 or 6; formula (III) and formula (IV) in which R3 represents hydrogen or an alkyl group and R4 represents an alkyl, methoxy, benzyl or R5NHCO group, R5 being an alkyl group; and Formula (V) in which R6 represents an alkyl group, and pharmaceutically acceptable salts thereof are useful in the treatment of migraine and other conditions. They are prepared by decarboxylation of the corresponding indolyl-2-carboxylic acid. |