Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02163ea9708e02ba34b0e29c190bd151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b326216374aaa7f194868834afbeb7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60a5429f966f4353c3c573f7852e4664 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
filingDate |
1993-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c63b2897bf2754933019ca9262359adb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c918b8510dc94cc2b2d515d22d9d521 |
publicationDate |
1994-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9401428-A1 |
titleOfInvention |
Asymmetric synthesis of hexahydrodibenzofurans by stereospecific inversion of ortho substituted 2-phenylcyclohexanols |
abstract |
This invention relates to the stereospecific process for the preparation, separation and purification of hexahydrodibenzofurans which are used in the preparation of the 5HT3 compounds. More specifically, the present invention relates to a process for the preparation of substantially optically pure cishexahydrodibenzofuran compounds including at least two chiral fused ring centers which comprises the acidic catalyzed stereospecific ring closure by the intra-molecular inversion of a gamma, i.e. 2', carbon atom of a 2-[(2'-leaving group)cycloalkyl]phenol. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8998720-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10454862-B2 |
priorityDate |
1992-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |