| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04b6164a7e1182729294f79d05e9efa1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1993-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59710b6c5c9947215c82907e5d409a40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8639ca9259b8388781557b91e7b1a1b |
| publicationDate |
1993-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9324658-A1 |
| titleOfInvention |
Signal amplification probe and methods of use |
| abstract |
A signal amplification probe for the detection of an immobilized target molecule in a sample. The probe contains 1) a transcription-based amplifier construct, and 2) a multivalent bridging molecule for direct or indirect attachment of the amplifier construct to the immobilized target molecule. The amplifier construct contains a polymerase promoter and a template for transcription by a polymerase that binds to the promoter. The signal amplification probe can be used in combination with either a capture probe for immobilizing the target molecule to a solid phase, a linker probe for attaching the multivalent bridging molecule to the target molecule, or both. Assays utilizing the probe and kits containing the probe are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9426934-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5981179-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0999285-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6203989-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0018962-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9426934-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6806047-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6027897-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9710364-A1 |
| priorityDate |
1992-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |