| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4db20dc89e8a7b4a45719d0dea6e0a06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1da5d9d1e91b2c6fca63ac6ae5603065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07b71571160c289fbf5fc680dfea513f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 |
| filingDate |
1993-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19cb031cb291c1f087dcdec0121b07b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b0706dbeec4d49f369624903387f9b6 |
| publicationDate |
1993-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9324109-A1 |
| titleOfInvention |
Palatable pharmaceutical compositions |
| abstract |
A pharmaceutical granular composition and method for taste masking bitter, unpleasant tasting drugs comprising a drug core and as a taste masking agent methacrylate ester copolymers. The method comprises coating the drug cores with separate layers of aqueous dispersions of the copolymers. Additionally, the coating composition may contain plasticizers and conventional excipients. The granules of the present invention can be used in the preparation of chewable tablets which have good palatability and bioavailability. Preferable copolymers are poly(ethylacrylate, methylmethacrylate) to which quaternary ammonium groups have been introduced to modify the permeability of the ester. The coating sytem of this invention releases the drug by diffusion and is influenced by drug solubility and media pH. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0236126-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0679391-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6932981-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0679391-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012041788-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6139865-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1235556-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1235556-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103221038-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8617587-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0016742-A1 |
| priorityDate |
1992-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |