http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9323049-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-10 |
| filingDate | 1993-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db239727aa1beffc43df51a6b126a135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c312be165aa31ea19ec87c28af9ac51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f37a38ddaad4a5bd17ffa51f334c82fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98d5aee8cc7dd69912b805ca0f3205c4 |
| publicationDate | 1993-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9323049-A1 |
| titleOfInvention | 3-(9-acridinylamino)-5-hydroxymethylaniline derivatives as anticancer agents |
| abstract | The present invention provides a compound having structure (I) wherein R?1 and R2¿ are independently the same or different and are hydrogen, an acetyl group; an acyl group having the formula -CO(CH¿2?)nCOCH3, wherein n = 1-3; -CO(CH2)nCOOM, wherein n = 1-4 and M is hydrogen, Na or K; or -(CH2)nCOOR, wherein n = 1-4 and R is hydrogen, Na, K or an alkyl group having 1 to 5 carbon atoms; a hydroxyalkyl group having the formula -(CH2)nCH2OH, wherein n = 1-4; a halo alkyl group having the formula -(CH2)nCH2X, wherein n = 1-4 and X is a chloro, bromo, or iodo group; a metal sulfonate (-SO3M) wherein M is Na or K; a metal sulfinate (-SO2M) wherein M is Na or K; an alkyl sulfonate (-SO3R) wherein R is an alkyl group having 1 to 4 carbon atoms such as methyl, ethyl, n-propyl or i-propyl; an alkylsulfonyl group (-SO2R) wherein R is an alkyl group having 1 to 4 carbon atoms such as methyl, ethyl, n-propyl or i-propyl; a metal alkylsulfonate having the formula -(CH2)nSO3M wherein n = 2-3 and M is Na or K; a metal alkylsulfate having the formula -(CH2)nOSO3M wherein n = 2-3, and M is Na or K; or a β-alanyl group. The present invention also provides a process for synthesizing the above-identified compound, intermediate compounds produced thereby, a pharmaceutical composition comprising the above compounds as well as a method for inhibiting growth of tumor cells using these compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109761898-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019513744-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109761898-A |
| priorityDate | 1992-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 437.