| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53e211d36ea18a28b99b1bc957d36990
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_067c1f6ec07067ca0b49b39431dd1631
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a67b02c2285bab6238acdbd735412f3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
| filingDate |
1993-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b70b14ababc681e2b94fbbbd09bf347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f8ef3d809c04e2b27f8726ac54f761c |
| publicationDate |
1993-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9320218-A1 |
| titleOfInvention |
Synthetic eukaryotic promoters containing two inducible elements |
| abstract |
Synthetic inducible eukaryotic promoters for the regulation of transcription of a gene achieve improved levels of protein expression and lower basal levels of gene expression. Such promoters contain at least two different classes of inducible elements, usually by modification of a native promoter containing one of the inducible elements by inserting the other of the inducible elements. In embodiments, additional metal responsive elements (MREs) and/or glucocorticoid responsive elements (GREs) are provided to native promoters, particularly the hMT-IIA and MMTV-LTR promoters. One or more constitutive elements may be functionally disabled to provide the lower basal levels of gene expression. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6071695-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10077420-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0049147-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0658627-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6410228-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6201165-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5731193-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100647490-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9428150-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11555172-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7960536-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701940-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9932658-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005046450-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9533831-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0658627-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6673768-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6657104-B1 |
| priorityDate |
1992-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |