http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9318064-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7449ca99fbf1c556219fe28876cbf2a9 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 |
filingDate | 1993-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd1e8e46f4b2bc0f96c34af0addcb80a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a512abb63dbd697fd996b22dcd82d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b794da56ed7d1c969a29b136071abd1 |
publicationDate | 1993-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9318064-A1 |
titleOfInvention | Endothelial cell-derived differentiation modulating factors, their preparation and use |
abstract | The invention provides a basic secreted polypeptide factor which has, if obtained from bovine aortic endothelial cells, an observed molecular weight, of from about 29 kD to about 34 kD on SDS-polyacrylamide gel electrophoresis using the following molecular weight standards: Phosphorylase b 97,400; Bovine serum albumin 60,000; Ovalbumin 45,000; Carbonic anhydrase 31,000; Soybean Trypsin Inhibitor 21,000; Lysozyme 14,000, which factor has the ability to promote the differentiation of 0-2A progenitor cells into type-2 astrocytes when applied to 0-2A progenitors growing in serum-free medium, and which promotion of astrocytic differentiation is more rapid when said factor is applied to 0-2A progenitors in the presence of CNTF or LIF. The invention includes formulations encompassing this factor and its prophylactic and therapeutic use. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0164239-A1 |
priorityDate | 1992-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.