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filingDate 1993-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a57c255b57b1bfe66bc269f3b935a54
publicationDate 1993-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9315723-A1
titleOfInvention Direct compression tablet excipient
abstract An excipient for use in the manufacture of directly compressed tablets is formed by mixing an aqueous solution of a water-soluble or water-dispersible film-forming binder with a molten C10-C26 fatty acid or ester thereof to form a colloidal solution and drying the colloidal solution or a mixture thereof with one or more additional excipient components. Preferably the film-forming binder is polyvinylpyrrolidone and the fatty acid or ester thereof is stearic acid. It is also preferred that a particulate hydrophobic tablet excipient, especially a hydrogenated vegetable oil, is present as an additional excipient component. Sticking and tablet weakness problems encountered when using hydrogenated vegetable oil as an excipient in direct tablet compression are overcome by using the hydrogenated vegetable oil in the form of an excipient in accordance with the present invention.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5458888-A
priorityDate 1992-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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