| abstract |
A novel SLe-type sugar chain derivative represented by general formula [I], which is useful as a medicine and has a novel structure containing moranoline, wherein R1 represents hydrogen, lower alkyl, lower alkenyl or lower alkynyl; R?2 and R3¿ represent each independently galactosyl, sialylgalactosyl or fucosyl; and R4 represents hydroxy or acetamido. This compound has the activity of inhibiting cell adhesion and inhibits secretin antagonistically, thus being useful for treating inflammation and its accompanying thrombosis, asthma and rheumatism, and for preventing and treating immunopathy and cancer. |