| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d6bbef4a8f092a74f69dd0dbdaa7170 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6957
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
1993-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_747c2c2e8ce8c6ae16090c0b75e6690c |
| publicationDate |
1993-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9313806-A1 |
| titleOfInvention |
Inactivation of cytotoxic drugs |
| abstract |
A three component kit of parts for use in a method of destroying target cells in a host is provided. The first component comprises a target cell-specific portion and an enzymatically active portion capable of converting a cytotoxic pro-drug into a cytotoxic drug. The second component is a cytotoxic pro-drug convertible by said enzymatically active portion to the cytotoxic drug. The third component comprises a portion capable of at least partly restraining the component from leaving the vascular compartment of a host when said compound is administered to the vascular compartment, and an inactivating portion capable of converting the cytotoxic drug into a less toxic substance. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5679394-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9513095-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0612240-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6140100-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9824478-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7138122-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9824478-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9513095-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9359439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6867231-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2883873-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9512176-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6319702-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0612240-A1 |
| priorityDate |
1992-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |