| abstract |
A quinolone derivative represented by general formula (1) or a salt thereof, and an antibacterial containing the same as the active ingredient, wherein R1 represents hydrogen or a protective group; R2 represents hydrogen, halogen or lower alkyl; X represents hydrogen or halogen; Y represents halogen, optionally substituted cyclic amino, optionally substituted lower cycloalkenyl, or R3-(CH2)m-A- wherein R3 represents hydrogen or optionally substituted amino, A represents oxygen or sulfur, and m represents a number of 0 to 3; Z represents nitrogen or C-R4 wherein R4 represents hydrogen or halogen; W represents an optionally substituted five-membered heterocyclic group having three or more heteroatoms among which at least two are nitrogen; and n represents a number of 0 to 2. This compound has a potent antibacterial activity and a high safety, thus being useful as human and animal drugs, medicines for fish, agricultural chemicals, and food preservatives. |