| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-15 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
1992-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98c910bf69d2c20134094b71340d0334 |
| publicationDate |
1993-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9309788-A1 |
| titleOfInvention |
Triplex forming oligonucleotide reagents targeted to the neu oncogene promoter and method of use |
| abstract |
A method for inhibiting the proliferation of cells which contain an erb B2/neu gene site. The method involves administering a therapeutic dose of an oligonucleotide which is capable of forming a colinear triplex with the promoter region of the erb B2/neu gene. The oligonucleotides can inhibit the CAT box, the TATA box or the linker domain between the CAT and TATA box or any combination of the these three. Specific oligonucleotides which will bind and form triplexes in this region are described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5955059-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8367628-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9587238-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815599-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1275398-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1275398-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9517507-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7094766-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6365345-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9393258-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9523162-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8183222-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6147056-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5523389-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5968748-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7033829-B2 |
| priorityDate |
1991-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |