| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55583 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
| filingDate |
1992-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0777adcd3295d4a3654c72dd9a0cc524
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca08e2b6cbfadc1283bf94b2eeeb4189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42ab3b475f326822b90963a5ee762b3f |
| publicationDate |
1993-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9307291-A1 |
| titleOfInvention |
Immunoglobulin d-associated glycans and uses thereof |
| abstract |
The receptor for IgD (IgD-R) on T lymphocytes has lectin-like properties and binds to carbohydrate moieties of IgD. Thus IgD-associated glycans bind to the IgD-R. Therefore, IgD-associated glycans, neoglycans comprising the IgD-associated glycans, and pharmaceutical compositions comprising these glycans are provided. The glycans and pharmaceutical compositions are useful in a method for inhibiting the binding of IgD to an IgD receptor, a method for inhibiting an immune response involving the interaction of T and B lymphocytes in a subject, and a method for treating a subject with an immune-mediated disease. Because the glycans can upregulate expression of IgD-R, they are also useful in a method for increasing the number of IgD receptors on the surface of a T lymphocyte, and in a method for enhancing an immune response in a subject being immunized with an antigen or vaccine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5834423-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0727216-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0727216-A1 |
| priorityDate |
1991-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |