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filingDate 1992-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1993-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9305147-A1
titleOfInvention Defective interfering hiv particles with chimeric cd4-env
abstract The subject invention relates to defective, interfering HIV particles and uses thereof. In particular, these particles encode a membrane bound receptor protein, as well as multitarget ribozymes, which together interfere with the production of infections HIV by a host cell by downregulating the amount of HIV envelope protein on the surface of the cell as well as the amount of HIV genomic RNA.
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