http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9302082-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-01 |
| filingDate | 1992-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374790642f0754a25c060a737a9b9d74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcac067daea7be3c098a7931b6557f3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12fdb23941c51e38a6f8a55160b88918 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a86b1c01d3c26ea23d9ce155a0ff3897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b152d762aa88010a19c07ff1184e793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76e4c22e610cab861d209c8ab6eca114 |
| publicationDate | 1993-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9302082-A1 |
| titleOfInvention | Cyclic ketal derivatives |
| abstract | Compounds are described of formula (I) (wherein R?1 represents a hydroxyl group or a group selected from -OCOCH=CHCH(CH3?)(CH2?)3?CH3?, -OCOCH=CHC(CH3?)=CHCH(CH3?)CH2?CH3? or -OCO-X-CH2?CH(CH3?)CH2?CH3? [where X is -CH=CHCH(CH3?)-, -CH2?CH(OH)CH(CH3?)-, -CH=CHC(OH)(CH3?)-, -CH2?CH(OH)CH2?- or -CH2?CH2?CH(CH3?)-]; R?2 represents a hydroxyl group or an acyloxy group selected from formyloxy and acetoxy; R?3 represents a group selected from (a) (where R?7 is a hydrogen atom or an acetyl group), -(CH3?)=CHCH(CH2?R?8)CH2?Ph (where R?8 is a hydrogen or a hydroxyl group), -C(CH2?OH)=CHCH(CH3?CH2?Ph, -C(=CH2?)CH(OH)CH(CH2?OH)CH2?Ph, -C(=CH2?)CH(NHCOCH3?)CH(CH3?)CH2?Ph, -C(CH2?NHCOCH3?)=CHCH(CH3?)CH2?Ph and (b); R?4, R?5 and R?6 may each independently represent a hydrogen atom or a methyl group; and salts thereof. These compounds inhibit the enzyme squalene synthase and/or are intermediates for the preparation of compounds which inhibit the enzyme squalene synthase. Compounds of the invention may be formulated for use in a variety of conditions where a lowering of the level of blood plasma cholesterol in animals would be beneficial and for use in combating fungal infections in animals. |
| priorityDate | 1991-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.