| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ac661be0b9a884290451af2b1432123 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-46 |
| filingDate |
1992-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35fd2832d915a872c6f9363e64fe9705 |
| publicationDate |
1993-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9301830-A1 |
| titleOfInvention |
Expression of enzymatically active recombinant human acetylcholinesterase and uses thereof |
| abstract |
The subject invention provides an enzymatically active, nonglycosylated, recombinant, human acetylcholinesterase comprising at least one polypeptide characterized by an amino acid sequence which is substantially identical to the amino acid sequence of naturally-occurring human acetylcholinesterase. The subject invention additionally provides an enzymatically active recombinant monomeric human acetylcholinesterase comprising a polypeptide characterized by an amino acid sequence in which serine is substituted for cys 611 in the sequence of narurally-occurring human acetylcholinesterase (position 580 in the mature polypeptide) and an enzymatically active recombinant human acetylcholinesterase comprising at least one polypeptide characterized by the presence of a methionine of the N-terminus of the amino acid sequence of naturally-occurring human acetylcholinesterase. The subject invention also provides therapeutic and diagnostic methods using the enzymatically active recombinant acetylcholinesterase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113637653-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113637653-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I688657-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113777088-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1072722-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113777088-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006076024-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006076024-A2 |
| priorityDate |
1991-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |