abstract |
The present invention relates to an isolated receptor-type tyrosine kinase, said tyrosine kinase characterised by, in its naturally occurring form, being reactive to monoclonal antibody III.A4, having an apparent molecular weight of approximately 120-150 kD in its glycosylated form and having an N-terminal amino acid sequence comprising E L I P Q P. More particularly, the present inventino relates to human eph/elk-like kinase (HEK). |