http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9222580-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a48b04f986c44c2ca9129ce0b1d17c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1a6435cacfc5e34054f71361232cd17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba1805c74463d14f6d059b5ce6ba9f0b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 1991-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33d5ca9405b2b66284e78dee19b3f90b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a896bf5377dd99c51ae9481da0c106 |
| publicationDate | 1992-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9222580-A1 |
| titleOfInvention | Novel human-origin neutrophil adhesion inhibitor and pharmaceutical composition containing the same |
| abstract | A novel human-origin neutrophil adhesion inhibitor having the following properties: (a) it is present in a platelet granule fraction and released from a cell by platelet activating stimulation, (b) it inhibits the adhesion of neutrophils to a substrate, (c) it inhibits the extension of neutrophils, (d) it has a molecular weight of 2,600 ± 260 kd according to gel filtration, (e) it has a molecular weight of 340 ± 34 kd and/or 190 ± 19 kd according to SDS-PAGE under reduction conditions, (f) it is deactivated when trypsinized, and (g) it has a partial amino acid sequence of Pro-Glu-Arg-Glu-Gln-Xaa-Lys. A pharmaceutical composition containing the same as the active ingredient is useful in treating chronic rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, rejection, reperfusion disturbance, chronic nephritis, chronic hepatitis, asthma, and so forth. |
| priorityDate | 1991-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 257.