| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-948 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-863 |
| filingDate |
1992-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_605c815f9f79d949832775e9a7eef347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_922ddd6f71ea9e89cfeeeac969e77cd0 |
| publicationDate |
1992-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9222327-A1 |
| titleOfInvention |
Double recombinant vaccinia virus vaccines |
| abstract |
Vaccines comprising a recombinant vaccinia virus expressing at least two heterologous genes encoding pathogen antigens are described. A first antigen gene is inserted into the thymidine kinase gene of the vaccinia virus and a second antigen gene is inserted into the hemagglutinin gene of the vaccinia virus. In particular, the hemagglutinin and fusion genes of the rinderpest virus have been inserted into the thymidine kinase and hemagglutinin genes of the vaccinia virus, respectively. Such double recombinant viruses have been found to be highly attenuated while remaining effective in protecting an inoculated host. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005047458-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2008264201-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9492534-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1489164-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8852927-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9005602-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2313807-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9944903-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865153-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584317-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005047458-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007014977-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149254-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463730-B2 |
| priorityDate |
1991-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |