| abstract |
The subject invention relates to methods for regulating wrinkles in mammalian skin comprising topical application of a lysophosphatidic acid compound having structure (1) or a cyclic derivative thereof having structure (2) or a pharmaceutically acceptable salt thereof, wherein -R is unsubstituted or substituted, saturated or unsaturated, straight or branched chain alkyl having from 12 to about 23 carbon atoms; each -X- is independently -O- or -S-; and -Y- is -O- or -CH2-. |