| abstract |
Quinoline derivatives of formula (I), wherein R1 is lower alkyl or aryl which may have suitable substituent(s), R2 is hydroxy, protected hydroxy, lower alkoxy, etc., R3 is hydrogen, lower alkyl, lower alkoxy(lower)- alkyl or ar(lower)alkyl and R8 is hydrogen, or R3 and R¿8? are linked together to form lower alkylene, R?4¿ is an organic group, Z is O or S, and n is 0, 1 or 2; and pharmaceutically acceptable salts thereof which are useful as a medicament. |