Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5d35cbcd18261ca6afc76a9f64ae2a1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
1992-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1087d946f00f61cdfbd77dc0271fcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d41dbba8605e4f10ed874a499ffc9932 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b51443f8defdeaf2600e137359a66769 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_240e1abd8fa75c2eda100f16b1b0258a |
publicationDate |
1992-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9215708-A1 |
titleOfInvention |
Methods for improving the sensitivity of hybridization assays |
abstract |
Methods for improving the sensitivity of hybridization assays which reduce non-specific binding (NSB) and non-specific hybridization (NSH) are disclosed. The methods include a washing method utilizing tetraalkylammonium salts at high temperatures, and release methods in which a probe-target complex is released from a solid support and recaptured. Use of both the washing and release methods results in substantial reduction in NSB and NSH without performing several rounds of release and recapture of the target nucleic acids. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2006244394-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9813527-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316352-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8460869-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0952228-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8399222-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6361940-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8951730-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006007567-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10829801-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0952228-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8034554-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006121888-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0029611-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0029611-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9813527-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6664045-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008539736-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7993853-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8551766-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006007567-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006121888-A3 |
priorityDate |
1991-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |