abstract |
The novel compounds of formulas (I) and (II), bicyclo 5,6-Dihydro-7H-pyrrolo-[1,2-a]-imidazol-7-ol and 7-one substituted ring systems, have been found to be useful inhibitors of the 5-lipoxygenase and cyclooxygenase enzymes, and cytokine suppressive agents, respectively, and therefore useful in the treatment and prophylaxis of disease states mediated thereby. |