abstract |
The invention concerns pharmaceutical formulations containing at least one pharmaceutically active substance in combination with a polymer of general formula (I) or (I'), in particular formulations for intravenous applications, in which R1?, R2?, R5? and R6?, which may be the same or different, are hydrogen or a methyl or ethyl group; Q is a valency bond, oxygen or an ester or amide bridge and Q' is hydrogen when Q is a valency bond or oxygen and a hydroxy or amino group when Q is an ester or amide bridge; x is a whole number from 3 to 50, preferably from 5 to 40, when Q is a valency bond or oxygen and a whole number from 3 to 1,000, preferably 50 to 100, when Q is an ester or amide function; G1? and G2?, which may be the same or different, are a valency bond, oxygen or an ester or amide group; n is a whole number from 4 to 44, preferably 12 to 16; y is a whole number from 2 to 50, preferably 10 to 40; and R3? is hydrogen or a lower-alkyl group with 1 to 6 C-atoms. |