| abstract |
Platelet activating factor antagonists of formula (I), wherein R1 is H or C¿1?-C4 alkyl optionally substituted by a substituent selected from phenyl, halophenyl, pyridyl, (C1-C4 alkoxy) carbonyl and di-(C1-C4 alkyl) amino, or is C2-C4 alkyl substituted by hydroxyl or by one ore two C1-C4 alkoxy groups or is (CH2)nCONR?7R8¿ where n is an integer from 1 to 4 and R?7 and R8¿ are each independently H or C¿1?-C4 alkyl, R?2¿ is selected from H, OH and C¿1?-C4 alkyl, R?3¿ is selected from halo and C¿1?-C4 alkyl, R?4¿ is methyl, and p is an integer from 0 to 3 and m is an integer from 0 to 3; or a pharmaceutically acceptable salt thereof. |