| abstract |
A non-infectious subunit vaccine for use against infectious laryngotracheitis virus (ILTV) comprises as active immunogen at least one glycoprotein of ILTV, or an immunogenic peptide derived therefrom, and optionally an adjuvant. Production of polypeptides displaying the antigenicity of ILTV glycoproteins by recombinant DNA means is disclosed. The disclosure extends to recombinant live virus vaccines containing gene sequences for ILTV glycoproteins, to recombinant ITL virus having heterologous DNA inserted into a non-essential region and to the use of ILTV promoter regions in recombinant virus. |