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filingDate 1991-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9819bd108ed9cb13604e6ae766e646
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publicationDate 1992-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9202485-A1
titleOfInvention Method for obtaining 2-nitrobenzaldehide derivatives and nitrobenzoic acid derivatives
abstract Method for obtaining 2-nitrobenzaldehide derivatives and nitrobenzoc acid derivatives having the formula (Ia?) (III) respectively, wherein R is H, C1-4? alkyl, C1-4? alkoxy or halogen. The method is comprised of selectively oxidizing a mixture of nitrobenzaldehide derivatives (I) with an aqueous solution of an oxidizing agent (II) wherein X is halogen, M is an alkaline or alkaline-earth metal and n is 1 or 2. Through said oxidation, 3-nitrobenzaldehide derivatives essentially are oxidized. 2-nitrobenzaldehide derivatives (Ia?) not oxidized may be removed through the use of a water-unmiscible solvent and the nitrobenzoc acid derivatives (III) may be precipitated in the aqueous phase by pH regulation. In a preferred mode of execution, 2-nitrobenzaldehide is of pharmaceutical interest as coronary dilator and 3-nitrobenzoc acid is of interest in the industry of dyes and in medicine as synthesis intermediary.
priorityDate 1990-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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