http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9113095-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
filingDate | 1991-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f84c8f7ce60c0ff2b1aa8f6db1bc61b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25e4aa073bde581b71e62dc0d3e19a33 |
publicationDate | 1991-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9113095-A1 |
titleOfInvention | Hypoxia-induced proteins including an activator of coagulation factor x and methods of preparation and use |
abstract | This invention provides a purified Factor X activator isolated from endothelial cell membranes, preferably a purified Factor X activator expression of which by a cell is reversibly induced by hypoxia or by sodium azide. An example is a purified Factor X activator comprising a polypeptide characterized by the ability to migrate as a single band and by an apparent molecular weight of between about 50,000 and about 150,000 daltons, preferably about 100,000 daltons, on a non-reduced SDS-polyacrylamide gel, loss of activity from exposure to mercury chloride, and an isoelectric focusing peak at a pH of about 5. Another characteristic of a purified Factor X activator is an optimum Factor X activating effect at a pH range of approximately 6.0-6.8. This invention also provides a purified nucleic acid molecule encoding a Factor X activator, and antibodies directed to Factor X activator. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6218179-B1 |
priorityDate | 1990-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.