| abstract |
A granulate, possibly pressed into the form of tablets, contains at least one insoluble, complex bound or barely soluble material in powder form, which can bind or neutralize acids, and which does not react with the acid of the effervescent system, and an effervescent system, consisting of at least one organic, edible acid and at least one alkaline or alkaline earth carbonate and/or bicarbonate. The active material is present in a quantity of 5 to 50 %, preferably 8 to 30 %, and in particular 12 to 25 % by weight. It has an acid binding power of between 2 and 40, preferably 3.5 to 25 mEq/g, does not react with the acid of the effervescent system and raises the pH value in 0.1 n HCl during 2 min. by a maximum of 0.5. It consists in particular of magnesium trisilicate, sucralfate and/or a bismuth salt. Each granule contains at least one acid component, at least one carbonate component and at least one active material bound to one another. The binding of the granulate components together is effected by a reaction product from an acid with a carbonate component and/or by at least one hydrocolloid, in particular xanthane, maltodextrin, galactomanane and/or tragacanth. |