http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9102539-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88fd9074e7f5629511f3a410b1316b5f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4732 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 1990-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b069691a728e6d7e01802c884855914 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780ada8fe69cac84f5a7b525a9cd5c84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6283406aaca8de1e74b46f1bae6ae60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f880aa1199355c587689c64b3b1d237 |
| publicationDate | 1991-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9102539-A1 |
| titleOfInvention | Method of obtaining, from casein beta, biologically active peptide enriched fractions, and peptide fractions thus obtained |
| abstract | In order to obtain, from casein $g(b), a partial hydrolyzate enriched with, firstly, a phosphopeptide or a 1-25 peptide fraction, and, secondly, precursors of $g(b)-casomorphine (these precursors being fragments which cover the 33-97 region of the casein $g(b) molecule), by hydrolyzing the casein $g(b) with a proteolytic enzyme, the hydrolysis is carried out in a saline medium, thereby causing a precipitate to appear in the medium and separating it from the soluble phase which represents the partial hydrolyzate desired. Preferably, this hydrolysis is carried out in a medium of which the ionic strength is equivalent to that of a solution of monovalent salt having an ionic strength of between 0.5 and 4M. In order to obtain the 1-25 peptide fraction and the precursors of $g(b)-casomorphine, ion exchange chromatography is carried out on this soluble phase, after having demineralized it by electrodialysis. In order to obtain the antihypertensive and immunostimulatory 177-183 peptide fraction, the precipitate obtained is made soluble, the resulting solution is brought to a pH level of between 6 and 9, and hydrolysis is carried out by means of a proteolytic enzyme. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0737690-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9724371-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9406306-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0737690-A2 |
| priorityDate | 1989-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.