| abstract |
9-fluor-postaglandine derivates are disclosed, having the formula (I), in which R1 represents the groups (a), (b), COOR4 or CONHR?5; R2 and R3¿ represent each a hydrogen atom or a free or functionally transformed hydroxy group; X represents a CH¿2? group, an O or S atom; W is hydrogen, -OR?6¿, halogen, -CN-, -NO¿2?, trifluoromethyl or COOR?6¿, and when R4 is hydrogen, their salts with physiologically tolerable bases. α-, β- or η-cyclodextrin-clathrates are also disclosed, as well as liposome-encapsulated compounds having the formula (I), their process of production and their pharmaceutical use. |