| abstract |
The invention relates to novel aminoalkyl maleimides of general formula (I) in which R1 and R2 are the same or different and represent hydrogen or a C1-C4 alkyl group and A is a straight or branched-chain, saturated or unsaturated alkylene chain with 2 to 6 carbon atoms, possibly interrupted by an oxygen or sulphur atom or carbonyl group, and their corresponding acid addition salts. The present invention also relates to the amidoalkyl maleimide derivatives formed from compounds of general formula (I) and immunological conjugates which may be produced by the conversion of amidoalkyl maleimide derivatives with peptides or proteins. The object of this invention is also the corresponding processes for making the compounds of the invention and the use of these conjugates in diagnostic determination methods, especially immunoassays. |