http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9014337-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15448ed04b7fbd4aa8acbc784faebcf9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-405 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-28 |
| filingDate | 1990-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09725a0bc54b58adc8e4ec26a3350321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe8f3f96a9f47eea90827377872dbcce |
| publicationDate | 1990-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9014337-A1 |
| titleOfInvention | Divalent metal salts of indomethacin |
| abstract | The present invention provides a method for the treatment of infllammation and pain in a mammal requiring such treatment, comprising administering to said mammal an anti-inflammatory and analgesically effective amount of an indomethacin salt of a divalent metal capable of forming a stable complex with indomethacin, or of a pharmaceutical composition comprising said indomethacin salt together with a pharmaceutically acceptable carrier, diluent and/or excipient. The present invention also provides a process for the preparation of an indomethacin salt of a divalent metal capable of forming a stable complex with indomethacin comprising forming a solution by dissolving indomethacin and a salt of said divalent metal in a tertiary amide or cyclic tertiary amide, adding a C1-4 alkanol or C3-6 ketone to the solution to precipitate the indomethacin metal salt and separating the indomethacin metal salt precipitate from the solution. The present invention still further provides a pharmaceutical composition for alleviating inflammation and pain comprising an anti-inflammatory and analgesically effective amount of salts of indomethacin produced by the process of the invention together with a pharmaceutically acceptable carrier, diluent and/or excipient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5466824-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2758819-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007026240-A1 |
| priorityDate | 1989-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.