Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-23 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
1990-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59c2e887010925e35e808fffdc8b3d69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6281fbb69f5c5a30b47e3745b7fe2330 |
publicationDate |
1990-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-9014097-A1 |
titleOfInvention |
Improved culture of human tumor-infiltrating lymphocytes by combining gas permeable bags and a primary culture container |
abstract |
There is disclosed a process for the enhanced expansion and maintenance of human tumor-infiltrating lymphocytes (TIL). The process comprises placing a human tumor sample in a primary culture container and maintaining the sample in the primary culture container for a period of time before transferring a substantial amount of the primary culture to a bulk culture container. The primary culture cells and/or conditioned medium retained in the primary culture container are periodically used to supplement the bulk culture. Both primary and bulk cultures are maintained and expanded by periodic addition of a suitable culture medium as needed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0491851-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0491851-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008099088-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008099088-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2911346-A1 |
priorityDate |
1989-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |