http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9006918-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b6bb811101b64c8c38adb44ea4f546c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-36 |
filingDate | 1989-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd37c1fe04e7618f62aa481d990310cd |
publicationDate | 1990-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-9006918-A1 |
titleOfInvention | A process for the preparation of 2,4- or 2,4,5-substituted 6-hydroxypyrimidines |
abstract | Preparation of 2,4- or 2,4,5-substituted 6-hydroxypyrimidines of formula (I), wherein R1 represents alkyl or NR7R8, R2 represents alkyl, aryl or aralkyl, and R?3, R7 and R8¿ each independently represents hydrogen, alkyl or aralkyl, or salts thereof with a salt-forming cation, by reacting a 3- or 2,3-substituted 3-aminoacrylic acid derivative of the formula (II), wherein X represents OR?4 or NR5R6¿, wherein R4 represents alkyl, aryl or aralkyl, and R?5 and R6¿ each independently represents hydrogen, alkyl or aralkyl, with a nitrile of formula: R1-C=N, in the presence of a base and a solvent, and, if desired, converting the salt formed to the free pyrimidine of formula (I) by adding an acid. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018030169-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0515265-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6281358-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6559307-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015036563-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0063183-A1 |
priorityDate | 1988-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.