| abstract |
An immunometric assay is disclosed for preselected monoclonal antibody in a biological sample comprising, forming a complex of a first labeled anti-idiotypic monoclonal antibody, the preselected monoclonal antibody, and a second anti-idiotypic monoclonal antibody which can be bound to an insoluble substrate and detecting the amount of labeled antibody associated with the complex. The assay is characterized by employing first and second monoclonal antibodies which react with an idiotypic site on the preselected monoclonal antibody. |