| abstract |
The present invention relates to nucleoside phosphate triesters and processes for their preparation. In particular, the present invention relates to nucleoside analogues of formula (I), where B = an organic base, X = -H or -N3, Z = -NR1R2, and Y = -OR?3 or NR4R5¿, wherein R?1, R2, R3, R4 and R5¿ are the same or different and are selected from -H, alkyl, aryl, acyl, substituted alkyl, substituted aryl and substituted acyl groups. |