| abstract |
A renin inhibiting compound of formula (I), wherein A is a substituent; R1? is hydrogen, loweralkyl, substituted loweralkyl or loweralkenyl; X is CH2?, CHOH, C(O), O, S, S(O), SO2?, NH, N(O) or -P(O)O-; R3? is loweralkyl, loweralkenyl or substituted loweralkyl; and T is mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof. |