| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525 |
| filingDate |
1989-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f77046cee66449056188689d4df6de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1140fe5228c2fe6e74684110a15da115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f64e3fdfb5652ebcbb5329be5ed7ae9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a601862d7268843b7b5df9f3e278a37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50bf2573d87ec93fd2060f88ec3b2b30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fb4d6589b89bfb9ccf42f71c3e018b8 |
| publicationDate |
1990-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9003395-A1 |
| titleOfInvention |
Novel physiologically active polypeptide, recombinant plasmid, recombinant microbial cells, medicinal composition, and process for recovering purified polypeptide |
| abstract |
The invention relates to novel physiologically active polypeptide of human tumor necrosis factor (human TNF) having modified terminal amino acids on both the amino terminal and carboxyl terminal, recombinant plasmid containing a DNA region coding said polypeptide, recombinant microbial cells transformed by said recombinant plasmid, a process for preparing said polypeptide by culturing said microbial cells, a medicinal composition containing said polypeptide and a process for purifying and recovering said polypeptide. This polypeptide has a better antitumor activity than the human TNF and can be utilized as an active ingredient of an antitumor composition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005042008-A1 |
| priorityDate |
1988-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |