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filingDate 1989-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1990-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-9001987-A1
titleOfInvention A method for carrying out organic chemical reactions and apparatus for carrying out that method
abstract In carrying out an organic chemical reaction, such as the synthesis of a polypetide, it is known to attach a substance to particles of pervious support material and to immerse the particles in a sequence of liquids which serve as reagents, solvents etc. The invention provides a method in which, during at least one stage in a reaction of that kind, a liquid is introduced into a vessel containing particles of support material in such a manner that the immediately preceding liquid is progressively displaced by the incoming liquid. Apparatus for carrying out that method comprises a vessel (1) with upper and lower sintered restraining plates (5 and 6) between which the support material is located. Valves (8 and 11) can be set at will to enable a pump (13) to pump liquid into the vessel from above or below and to recirculate or discharge the liquid.
priorityDate 1988-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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