http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9001488-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab8466bce065232b391d77292152f21f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 |
| filingDate | 1989-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_061cecdac096182b45fe75a36b431525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c97f75694b96a449612fb1d626b4f0a |
| publicationDate | 1990-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9001488-A1 |
| titleOfInvention | Synthetic receptor analogues |
| abstract | Compounds of general formula (I), wherein R1 is alkyl; alkenyl; alkynyl; tri(alkyl)silylethyl; optionally substituted aryl; mono- or di-halogenalkyl; phenylalkyl; a group of formula (II): R3-(CH2)n-S(O)m-CH2CH2- or formula (IIa): (R3-(CH2)n-S(O)m-CH2)2CH-CH2-, wherein R3 is H, carboxy, carboxyalkyl, hydroxy, amino, or a carrier, n is an integer from 1 to 24, and m is 0 or 2; a group of formula (III): Phe-S(O)m-CH2CH2- or formula (IIIa): (Phe-S(O)m-CH2)2CH-CH2- wherein each Ph is an optionally monosubstituted phenyl group; a group of formula (IV): R4CH2CH(CH2R5)CH2- wherein R4 and R5 independently are halogen; a group Q-(CH2)n- where Q is a carrier; and R2 is a mono- or disaccharide moiety connected via a glycosidic bond; alkyl; alkenyl; alkynyl; alkyloxymethyl; alkanoyl; alpha -hydroxy-alkanoyl; optionally substituted naphthyl-, heterocyclyl- or phenylalkoxy; a trialkylsilyl-containing group; halogen; omega -hydroxy-C1-4alkyl; tetrahydropyranyl; benzyloxymethyl; cycloalkyl; a monoterpenyl moiety; optionally monosubstituted benzoyl; the acyl residue of a naturally occurring amino acid; or a group of formula (V): R6-C(O)-N(R7)-CH(R8)-CH2-, wherein R6 is C1-4 alkyl; or optionally monosubstituted phenyl, R7 is H or C1-4 alkyl, and R8 is H, C1-4 alkyl, or hydroxy-C1-4 alkyl, Z is -O-, -S-, -SO2-, or -CH2-, X is -O-, -S-, -SO2-, -CH2-, or -NR3-, wherein R3 is H or is one of the meanings for R2 above, R3 and R1 optionally being connected to form a ring, and Y is -O- or -NR3- where R3 and R2 optionally are connected to form a ring. Compounds of general formula (I) have enhanced receptor binding properties to bacteria and are useful in inhibiting the binding of bacteria to mammalian cell surfaces. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6037467-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5409902-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0601417-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0551674-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0601417-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5856416-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0518270-A1 |
| priorityDate | 1988-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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