http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8912466-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d37ee2b287608113ae9808dfdfc42b9a
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0006
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
filingDate 1988-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1237e2e45f8a4fdf4921ce543aafe110
publicationDate 1989-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-8912466-A1
titleOfInvention Cancer detection preparations and method
abstract A method for detecting cancer comprises intradermally injecting into a patient a test preparation comprising a glycoprotein-polysaccharide-like antigenic substance admixed with the patient's blood serum. The patient's serum is also injected intradermally as a control and the physical dimensions of the erythemas of the injections measured and compared as an indication of the presence of cancer. An initial antigenic substance is derived from cancerous tissues by disintegrating the tissue to enable the separation of the nuclei and cell membranes from the mitochondrial fraction of the cell. After lipids are removed from the mitochondrial fraction, it is hydrolyzed in hot alkali, dialyzed and then deproteinated. The cancer specificity of the antigenic substance is enhanced by gel filtration. Prior to admixture with the antigenic substance, the blood serum is subjected to an adsorptive procedure to remove non-cancerous antibodies which might otherwise be reactive with the antigenic substance. A proteolytic enzyme (e.g trypsin) is added to a portion of the blood serum: to provide, in the preferred embodiment, additional cancer detection preparations.
priorityDate 1978-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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