http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8909766-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-08 |
| filingDate | 1989-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c728980c43200b72d892f2e30a04eee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff2d2ce96bf458a338790fcabadfce94 |
| publicationDate | 1989-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-8909766-A2 |
| titleOfInvention | Process for the preparation of 2,4,6-triiodo-5-amino-n-alkylisophthalamic acid |
| abstract | An improved process for preparing a compound selected from among 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid, salts thereof and esters thereof. A substrate selected from among 5-amino-N-alkylisophthalamic acid, salts thereof and esters thereof is reacted with an iodine halide in an aqueous reaction medium. In accordance with the improvement, the substrate and a source of the iodine halide are added to the reaction medium at such relative rates that, at any instant substantially throughout the addition cycle, the substrate is present in stoichoimetric excess over the iodine halide, but the difference between the cumulative amount of the substrate that has been added to the medium at such instant, expressed as a proportion of the total ultimate charge of the substrate, and the cumulative amount of the source of iodine halide that has been added to the medium at such instant, expressed as a proportion of the total ultimate charge of the source of iodine halide, does not exceed 10 %. Further improvements, respectively comprising incorporation of an alkaline buffer and operation at relative high dilution, are also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0484328-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE38856-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9852909-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9852908-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6274762-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6137006-A |
| priorityDate | 1988-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.