| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf48a2acfbc3e9091bb3d819ea517db0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6018 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
1989-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229075ec20b7deabd98e4f32eecc8a35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5956bb3469355d54ff2de0b694c1281
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b831ecd9227198eccfb43a5d3a88cc5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_611c3cdb1c85f40fd620c28e466ed0ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2bdb4dd409b6c2cfe0e33788a8aec22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ede223d114594bfe2bc9efefc5827100 |
| publicationDate |
1989-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-8908711-A1 |
| titleOfInvention |
Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates |
| abstract |
A method of producing monoclonal antibodies that bind to human cancer-associated mucin-type glycoprotein antigens comprising: (1) immunizing a host with a core structure of a mucin-type glycoprotein; (2) fusing splenocytes from said immunized host with myeloma cells to form hybridoma cells; (3) culturing said hybridoma cells on selective medium; (4) selecting hybridoma cells surviving step (3) that secrete antibody that binds to said core structure of a mucin-type glycoprotein; (5) cloning said selected hybridoma cells from step (4); (6) culturing said cloned hybrodoma cells; and (7) recovering said antibody. Hybridomas and monoclonal antibodies produced by the above-described method. Methods of passive and active immunization employing the monoclonal antibodies and mucin-type glycoproteins or synthetic oligosaccharide-carrier conjugates. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9518145-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5876716-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6156881-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6613746-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8771701-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0512023-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9111528-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11161911-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5837830-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0052046-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0512023-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5989552-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6548643-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-653141-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5723583-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5801044-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5527891-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5858983-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8021667-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113287018-A |
| priorityDate |
1988-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |