Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0bf0e2b67d21b775ccc2a0b049599cd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
filingDate |
1989-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7930ac1749a9cb238d9fbad5d9b06ed1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_416c9a39aa894290e0f539205febe156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a2fbcaa044cfc5060ed499beaae04d |
publicationDate |
1989-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-8907114-A1 |
titleOfInvention |
Novel and improved antibodies for site specific attachment of compounds |
abstract |
Novel and improved antibody compositions comprising an antibody or antibody fragment having an increased number of sites on a carbohydrate side chain available for the site specific attachment of a compound to a region of the antibody or antibody fragment which is not part of nor directly involved with the antigen binding site are disclosed. Conjugates, prepared using the high-mannose-containing antibodies, which are characterized by substantially the same immunospecificity as the unmodified unconjugated antibody molecule, are also disclosed. The antibody compositions are advantageously used for a wide variety of therapeutic and diagnostic applications in both in vivo and in vitro targeted delivery systems and assays. Methods for preparing the antibody compositions, as well as antibody conjugate intermediates, and methods for using the antibody compositions are also described. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0419387-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5274076-A |
priorityDate |
1988-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |