abstract |
The invention relates to molecular biology. The substances - 5'-phosphonates 3'-azido-2',3'-dideoxynucleosides - have the following general formula (I), where R = (a), (b), (c), where B is thymine-1-yl, cytosine-1-yl, adenine-9-yl, guanine-9-yl. The substances are selective inhibitors for reproduction of the human immunodeficiency virus in this culture of human lymphocytes. |