Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1ca2fe5a1e9022aa0323cbb48d30f5e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-445 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-20 |
filingDate |
1988-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98f75d8e8ba0b3de46538ffdc5d15fdb |
publicationDate |
1989-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-8901785-A1 |
titleOfInvention |
Monoclonal antibodies to a plasmodium falciparum protein |
abstract |
Continuous hybridoma cell lines have been produced that secrete monoclonal antibodies to the PfHRP-II antigen of blood stage P.falciparum. One of these, designated MAb 87-2B2, is of the IgM isotype. MAb 87-1D6, MAb 87-1D10, MAb 87-2G12, and MAb 87-1E1 are of isotype IgG1 or IgM. The monoclonal antibodies of the present invention are well suited for use in immunometric assays for the quantitative and qualitative detection of the PfHRP-II antigen. Also disclosed are anti-idiotypic and anti anti-idiotypic antibodies to the monoclonal antibodies of the present invention. The antibodies and antigen of the present invention are useful for immunodiagnostic and immunotherapeutic treatment of P.falciparum malaria in animals, including humans. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8556843-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5478741-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-683000-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8367807-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8367350-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9015621-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8846048-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0588122-A1 |
priorityDate |
1987-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |