| abstract |
A new, human proteinaceous lymphokine denominated cytotoxicity triggering factor (CTF) as are methods of its preparation and use. Substantially pure CTF has an apparent Mr? of about 55 kd, is capable of inducing secretion of a tumor-killing factor containing tumor necrosis factor-alpha from primed monocytes, and is substantially free from pyrogen as well as interferon-gamma, interleukin-2 and direct cytotoxin. |